PO-029 Advances in research on hypoxia-mediated miRNAs affecting glucose metabolism
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چکیده
منابع مشابه
Advances in glucose metabolism research in colorectal cancer
Cancer cells uptake glucose at a higher rate and produce lactic acid rather than metabolizing pyruvate through the tricarboxylic acid cycle. This adaptive metabolic shift is termed the Warburg effect. Recently progress had been made regarding the mechanistic understanding of glucose metabolism and associated diagnostic and therapeutic methods, which have been investigated in colorectal cancer. ...
متن کاملAdvances in Hypoxia-Mediated Mechanisms in Hepatocellular Carcinoma.
Hepatocellular carcinoma (HCC) is the fifth most common and the third most deadly malignant tumor worldwide. Hypoxia and related oxidative stress are heavily involved in the process of HCC development and its therapies. However, direct and accurate measurement of oxygen concentration and evaluation of hypoxic effects in HCC prove difficult. Moreover, the hypoxia-mediated mechanisms in HCC remai...
متن کاملHyperglucagonemia and insulin-mediated glucose metabolism.
The effect of chronic physiologic hyperglucagonemia on basal and insulin-mediated glucose metabolism was evaluated in normal subjects, using the euglycemic insulin clamp technique (+50, +100, and +500 microU/ml). After glucagon infusion fasting glucose increased from 76 +/- 4 to 93 +/- 2 mg/dl and hepatic glucose production (HGP) rose from 1.96 +/- 0.08 to 2.25 +/- 0.08 mg/kg X min (P less than...
متن کاملEffect of maternal variable stress on oxidative status and glucose metabolism in pubertal male rats
Introduction: Metabolic disorders are affected by negative stress experiences in the early stages of life. Accordingly, in this study, the effects of stress during pregnancy on oxidative status and glucose homeostasis in pubertal male Wistar rats were investigated. Materials and Methods: After pregnancy, female rats (200±30 g) were divided into 2 groups (6 rats per group) of stress and non-stre...
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ژورنال
عنوان ژورنال: Exercise Biochemistry Review
سال: 2018
ISSN: 2593-7588
DOI: 10.14428/ebr.v1i3.9933